From Brooklyn:
From the Brooklyn battery Tunnel   
Turn right onto West Side Highway/West street
Turn slight right onto Canal street
Turn left onto Holland Tunnel
Follow directions from Holland Tunnel  

From New Jersey Turnpike
Go to Exit 15W (280W)
Take 280W to Exit 6A

From the Garden state Parkway
Take exit 145 to I-280W toward the Oranges
Take exit 6A, Laurel Ave South.

From Varazzano Bridge:
Take the I-278/VERRAZANO BR exit- EXIT 3- toward STATEN ISLAND.
Follow signs to Goethals Bridge
Take the I-95 N/TURNPIKE NORTH exit on the LEFT.
Merge onto NEW JERSEY TURNPIKE N/I-95 N toward CARS/TRUCKS - BUSES (Portions toll).
Follow Directions to Exit 15W 280W  

From Holland Tunnel: 
Take the Holland Tunnel to N.J.
Continue straight, at the last set of lights stay on the two left lanes.
Follow the signs to 1-9 South (Truck Route).
Take 1-9 South towards the Pulaski Skyway. Take the lower roadway but DO NOT GO OVER SKYWAY.
Make a right at 2nd exit (Kearny, Harrison Newark) 280.
Continue straight towards traffic circle(Exxon station on right). Bear right follow signs to 280, Harrison, NJ Turnpike.
Go over a small steel bridge continue for 2-3 miles and you will see signs for 280 west.
It's about 3/4 mile passed a very Large Post Office on the left.
Take 280W to exit 6A.

From George Washington Bridge:
Take New Jersey Turnpike south
Take exit 15W – Rt 280 W

From Lincoln Tunnel:
Take the LINCOLN TUNNEL toward NEW JERSEY
Merge onto I-495 W.
Take New Jersey Turnpike south.
Take exit 15W – Rt 280 W